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FOI 0156 2019/20 Types of Cancer Treatment

Freedom of Information Request 0156 2019/20

 

I am writing to you today to request the following information regarding Cancer Treatments at your organisation.

  1. Does your trust treat adult multiple myeloma [MM] ? – if you refer your multiple myeloma patients to another centre, please state which.
  2. If yes, then how many MM patients, have been treated in the past 6 months with the following;
  • Bortezomib [Velcade]
  • Carfilzomib [Kyprolis]
  • Ixazomib [Ninlaro]
  • Lenalidomide [Revlimid]
  • Daratumumab [Darzalex]
  • Melphalan, prednisolone and thalidomide (known as MPT)
  • Cyclophosphamide, thalidomide and dexamethasone (known as CTD)
  • Pomalidomide [Imnovid]
  1. If you are able to split by therapy line for question 2, please indicate the number of patients above being treated, 1st line and 2nd line.
  2. Does your trust treat adult/paediatric primary immune thrombocytopenia patients [ITP] ? – if you refer your adult/paediatric primary immune thrombocytopenia patients to another centre, please state which.
  3. If yes, then of the treated adult/paediatric primary immune thrombocytopenia patients, how many are on the following;
  • Eltrombopag [Revolade]
  • Romiplostim [Nplate]
  1. At what line of treatment would you currently use a Thrombopoietin Receptor Agonist [TPO] (Eltrombopag [Revolade], Romiplostim [Nplate]) in an immune thrombocytopenia purpura [ITP] patient.
  • 1st
  • 2nd
  • 3rd
  • 4th
  • Unknown
  1. Do you treat patients with a Thrombopoietin Receptor Agonist TPO for the following diseases?

7a. Chronic hepatitis C virus (HCV) infection for the treatment of thrombocytopenia, where the degree of thrombocytopenia is the main factor preventing the initiation or limiting the ability to maintain optimal interferon-based therapy

  • Eltrombopag [Revolade]
  • Romiplostim [Nplate]

7b.Acquired severe aplastic anaemia (SAA) who were either refractory to prior immunosuppressive therapy or heavily pre-treated and are unsuitable for haematopoietic stem cell transplantation

  • Eltrombopag [Revolade]
  • Romiplostim [Nplate]

7c. Chemotherapy induced thrombocytopenia (CIT)

  • Eltrombopag [Revolade]
  • Romiplostim [Nplate]
  • 7d myelodysplastic syndromes (MDS)
  • Eltrombopag [Revolade]
  • Romiplostim [Nplate]
  1. Over the past 6 months [latest possible], how many chronic lymphocytic leukaemia (CLL) patients have you treated?
  2. If possible how many CLL patients treated were new to therapy in the past 3 months?
  3. How many chronic lymphocytic leukaemia patients, have been treated in the past 6 months with the following;
  • Fludarabine (Fludara), cyclophosphamide (Cytoxan), and rituximab (known as FCR)
  • Bendamustine and rituximab (known as BR)
  • Ibrutinib [Imbruvica]
  • Chlorambucil
  • Venetoclax
  • Obinutuzumab
  • Idelalisib
  • Fludarabine and rituximab (known as FR)
  • High-dose prednisone and rituximab
  • Pentostatin (Nipent), cyclophosphamide, and rituximab (known as PCR)
  • Alemtuzumab (Campath) with rituximab

Please see attached document

FOI 0156

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