Freedom of Information Request: 0357 2019/20

1) Does your Trust routinely offer Mass Spectrometry testing for Diagnostic purposes? (Please answer either yes or no to this question).

Yes

2) If you answered yes to question 1, can you please provide a list of which assays / tests are routinely run on the Mass Spectrometry system in your Trust.

Queen Elizabeth Hospital Birmingham

• Steroids (Androstenedione, 17-hydroxyprogesterone and testosterone)
• Aldosterone
• Immunosuppressants (Ciclosporin, Tacrolimus, Sirolimus, Everolimus)
• Urinary free cortisol
• Salivary cortisol
• Lysoglobotriaosylsphingosine (Lyso GB3)

Heartlands, Good Hope and Solihull

• Vitamin D
• Testosterone (female)
• Homoecysteine
• Urine catecholamines and metanephrines
• Plasma metanephrines
• Urine free cortisol
• Prednisolone
• Dexamethasone
• TPMT metabolites
• Toxicology:
  • Aluminium
  • Arsenic
  • Cadmium
  • Chromium
  • Cobalt
  • Copper
  • Lead
  • Manganese
  • Selenium
  • Urine Copper
  • Zinc
  • Alprazolam
  • Amisulpride
  • Aripiprazole
  • Amfetamine
  • Beta-hydroxybutyrate
  • Buprenorphine & Norbuprenorphine
  • Citalopram and Desmethycitalopram
  • Clobazam
  • Clozapine
  • Cocaine & BZE
  • Codeine
  • Cotinine
  • Diazepam, Nordiazepam, Oxazepam and Temazepam
  • Dihydrocodeine
  • Duloxetine
  • Ethylene and diethylene glycol
  • Etizolam
  • Fentanyl
  • Fentanyl Analogue Screen
  • Fluoxetine
  • Gabapentin
  • Gamma-hydroxybutyrate
  • Haloperidol
  • Levetiracetam
  • Lithium
  • Lorazepam
  • MDMA/MDA
  • Metamfetamine
  • Methadone
  • Midazolam and 1-hydroxymidazolam
  • Mirtazapine
  • Morphine, Morphine-3-glucoronide, morphine-6-glucoronide
  • Olanzapine
  • Oxycodone
  • Paroxetine
  • Pregabalin
  • Quetiapine
  • Risperidone & 9-hydroxy risperidone
  • Sertraline
  • Valproate
  • Venlafaxine / ODV
  • Bromazepam*
  • Urine drugs of abuse testing
  • Unknown toxicology screening
  • Antihypertensive drug screening

3) Does your Trust send away samples (to locations outside of your trust) for Mass Spectrometry testing? (Please answer either yes or no to this question).

Yes

4) If you answered yes to question 3, can you please list the assays / tests which are run on the samples you send away?

• Carnitine + Acylcarnitines
• Dihydrotestosterone
• Methylmalonic acid (MMA)
• Mitotane
• Mycophenolate mofetil
• Organic acids
• Orotic acid
• Phenylalanine (PHE)
• Succinylacetone
• Trimethylaminuria
• Urine steroid profile
• Very long chain fatty acids (VLCFAs)
• Synthetic Cannabinoid Testing