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FOI 0655 Cutaneous Squamous Cell Carcinoma 2019/20

Freedom of Information Request: 0655 2019/20

University Hospitals Birmingham NHS Foundation Trust (UHB) completed a merger by acquisition of Heart of England NHS Foundation Trust (HEFT) on 1st April 2018.  Due to historical differences in data collection/reporting across UHB and the former Heart of England NHS Foundation Trust this response has been provided by hospital site.

Queen Elizabeth Hospital Birmingham:

  1. How many patients with cutaneous squamous cell carcinoma have you treated [eg surgery, chemotherapy or radiotherapy] in the past 3 months?

382

  1. How many adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma have you treated [eg surgery, chemotherapy or radiotherapy] in the past 3 months?

34

  1. Of these how many are not candidates for curative surgery or curative radiation?

We do not hold this information

  1. In the past 3 months, how many adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma who are not candidates for curative surgery or curative radiation have you treated with the following;

Libtayo (cemiplimab)   0

Non curative surgery only   0

Non curative surgery + chemotherapy*   0

Non curative surgery + radiotherapy     0

Non curative surgery + chemotherapy* + radiotherapy     0

Chemotherapy* only   24

Chemotherapy* + radiotherapy   0

Non curative radiotherapy only    0

No treatment   0

Palliative Care / Best Supportive care   0

Other [please state]

*chemotherapy such as cisplatin, doxorubicin, 5-fluorouracil (5-FU), capecitabine, topotecan, or etoposide

  1. Does your trust treat adult multiple myeloma [MM]?

Yes

– if you refer your multiple myeloma patients to another centre, please state which.

N/A

  1. If yes, then how many multiple myeloma patients, have been treated in the past 6 months with the following;

Bortezomib [Velcade]    9

Carfilzomib [Kyprolis]   0

Ixazomib [Ninlaro]         1

Lenalidomide [Revlimid]   11

Daratumumab [Darzalex]  7

Melphalan, prednisolone and thalidomide (known as MPT)   0

Cyclophosphamide, thalidomide and dexamethasone (known as CTD)   1

Pomalidomide [Imnovid]   4

  1. Over the past 6 months [latest possible], how many chronic lymphocytic leukaemia (CLL) patients have you treated?

If possible how many CLL patients treated were new to therapy in the past 3 months?

We do not hold this information

  1. How many chronic lymphocytic leukaemia patients, have been treated in the past 6 months with the following;

Fludarabine (Fludara), cyclophosphamide (Cytoxan), and rituximab (known as FCR) 1

Bendamustine and rituximab (known as BR)   0

Ibrutinib [Imbruvica]   4

Chlorambucil   0

Venetoclax   2

Obinutuzumab   0

Idelalisib   0

Fludarabine and rituximab (known as FR)   1

High-dose prednisone and rituximab   0

Pentostatin (Nipent), cyclophosphamide, and rituximab (known as PCR)   0

Alemtuzumab (Campath) with rituximab   0

 

Heartlands, Good Hope and Solihull Hospitals:

  1. How many patients with cutaneous squamous cell carcinoma have you treated [eg surgery, chemotherapy or radiotherapy] in the past 3 months?
  2. How many adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma have you treated [eg surgery, chemotherapy or radiotherapy] in the past 3 months?
  3. Of these how many are not candidates for curative surgery or curative radiation?
  1. In the past 3 months, how many adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma who are not candidates for curative surgery or curative radiation have you treated with the following;

Libtayo (cemiplimab)

Non curative surgery only

Non curative surgery + chemotherapy*

Non curative surgery + radiotherapy

Non curative surgery + chemotherapy* + radiotherapy

Chemotherapy* only

Chemotherapy* + radiotherapy

Non curative radiotherapy only

No treatment

Palliative Care / Best Supportive care

Other [please state]

*chemotherapy such as cisplatin, doxorubicin, 5-fluorouracil (5-FU), capecitabine, topotecan, or etoposide

Due to historical differences in information systems across the two former Trusts, we do not hold the information requested in questions 1-4 in a format that allows us to provide it for Heartlands, Good Hope or Solihull Hospitals.

  1. Does your trust treat adult multiple myeloma [MM]?

Yes

– if you refer your multiple myeloma patients to another centre, please state which.

N/A

  1. If yes, then how many multiple myeloma patients, have been treated in the past 6 months with the following;

Bortezomib [Velcade]   2 (with Daratumumab – 7)

Carfilzomib [Kyprolis] 1

Ixazomib [Ninlaro]   1 (with Lenalidomide – 18)

Lenalidomide [Revlimid]   19 (with Ixazomib – 18)

Daratumumab [Darzalex]   10 (with Bortezomib – 7, Pomalidomide – 1)

Melphalan, prednisolone and thalidomide (known as MPT)  0

Cyclophosphamide, thalidomide and dexamethasone (known as CTD)   1

Pomalidomide [Imnovid]   4

  1. Over the past 6 months [latest possible], how many chronic lymphocytic leukaemia (CLL) patients have you treated?

If possible how many CLL patients treated were new to therapy in the past 3 months?

            We do not hold this information

  1. How many chronic lymphocytic leukaemia patients, have been treated in the past 6 months with the following;

Fludarabine (Fludara), cyclophosphamide (Cytoxan), and rituximab (known as FCR)   0

Bendamustine and rituximab (known as BR)   0

Ibrutinib [Imbruvica]   6

Chlorambucil   1 (with Obinutuzumab – 1)

Venetoclax   2

Obinutuzumab (with Chlorambucil – 1)

Idelalisib   0

Fludarabine and rituximab (known as FR)   0

High-dose prednisone and rituximab   0

Pentostatin (Nipent), cyclophosphamide, and rituximab (known as PCR)    0

Alemtuzumab (Campath) with rituximab   0

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