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FOI 3251 New Anti Coagulants NOACs

The response to your query is detailed below:

  • Numbers of patients treated with the new oral anti-coagulation treatments:

 

Drug Number patients treated in the last 3 months
Rivaroxaban (Xarelto) 166
Dabigatran (Pradaxa) 50
Apixaban (Eliquis) 71

 

 

 

 

 

  • What is the usual dose/strength for the following treatments, for each of the indications listed:
Drug Typical does for VTE prophylaxis Typical dose for ACS Typical dose for AF
Rivaroxaban (Xarelto) As per NICE/BNF: 10mg BD Not used As per NICE/BNF: 20mg OD
Dabigatran (Pradaxa) As per NICE/BNF: 110mg STAT then 220mg OD Not used As per NICE/BNF: 150mg BD
Apixaban (Eliquis) As per NICE/BNF: 2.5mg BD Not used As per NICE/BNF: 5mg BD

 

  • If possible, please split the patients by the following diagnosis;

 

Drug Acute cardiac syndrome (ACS)

 

Venous Thrombo-embolism (VTE) Prophylaxis of VTE
Rivaroxaban (Xarelto) We are not able to split prescription by diagnosis
Dabigatran (Pradaxa)
Apixaban (Eliquis)

 

  • Please fill in the following table relating to dispensed items in the last 3 months:
Drug & strength Number of items dispensed from pharmacy
Rivaroxaban (Xarelto) 20mg 107.75 boxes of 28
Rivaroxaban (Xarelto) 10mg 15.9 boxes of 30
Rivaroxaban (Xarelto) 15mg 141.04 boxes of 28
Dabigatran (Pradaxa) 110mg 18.07 boxes of 60
Dabigatran (Pradaxa) 75mg Not Kept
Dabigatran (Pradaxa) 150mg 31.80 boxes of 60
Apixaban (Eliquis) 2.5mg 45.7 boxes of 60
Apixaban (Eliquis) 5mg 32.75 boxes of 56

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