1. Please can you send me a link to your transplant guidelines? I would like to know what tacrolimus is used and why?

Please see attached. SOP 008 V9 I1 Management of GvHD in allo recipients AK

This document is intended to develop a standard operating procedure for the management of graft versus host disease occurring in recipients of allogeneic blood progenitor cell transplants at Birmingham Heartlands Hospital.

We use tacrolimus as second line immunosuppression if the patient experiences significant side effects with ciclosporin (severe allergic reactions, hypertension, renal or hepatic impairment, fluid retention, evidence of ciclosporin related TTP).

2. Also could you tell me who is on the Drugs and therapeutics committee please?

 Tania Carruthers – Clinical Director of Pharmacy
 Carol Evans – Interfacing Prescribing Manager
 Yogita Chikermane – Consultant Anaesthetics
 Gurdeep Chopra – Principal Pharmacist – Clinical Effectiveness & Medication Safety
 Katy Davies – Pharmacist – Medicines Information
 Siljia Eveson – Midwife
 Kavita Gopee – Nurse
 Scott Hackett – Consultant Paediatrics/Neonates
 Natasha Jacques – Principal Pharmacist – Specialised Medicine & Community Services
 Karen Ennis – Assistant Head of Medicines Management CCG
 Nilima Rahman-Lais – Deputy Head of Medicines Management CCG
 Charalampos Kartsios – Consultant Haematology
 Caroline Maynard – Faculty Nurse Educator
 Shahzad Razaq – Principal Pharmacist – Medicine and Anti-Infectives
 Ellen Shirley – Principal Pharmacist – Cancer Services
 Vijayan Suresh – Consultant Renal
 Su Dorrian – Consultant Emergency Department
 Rachel Ferreday – General Manager Division 1
 Tim Priest – Consultant Anaesthetist